In vitro release testing and in vitro permeation testing are effective means of evaluating the performance of semi-solid dosage. They can discern the impact of formulation and process changes on the dosage, making them important tests for quality control in semi-solid formulation development and stability assessment.

The FOCSFVDT-1202C Automated Transdermal Diffusion System uses a diffusion cell structure compliant with the C-model in USP1724 standards. It offers user-friendly operation, delivers stable and consistent test results, and facilitates research related to topical formulations.

This system is equipped with 12 independent vertical diffusion cells, featuring automated degassing, temperature measurement of the receiving liquid in the diffusion cell, infrared temperature measurement of the membrane, automated maintenance of constant liquid level for sampling, and solvent replenishment functions. It incorporates advanced automated sampling technology, enabling complete automation of sample collection, filtration, sample retrieval, and sovlent replenishment. It is a fully automated instrument for in vitro release testing and in vitro permeation testing, supporting the development and quality control of semi-solid dosage forms.

Diffusion cells that comply with USP1724 Standard;

Automatic venting function, preventing sub-membrane bubbles from affecting test results;

Each diffusion cell is equipped with an independent high-precision infrared temperature sensor to monitor membrane temperature in real-time (optional);

Patented design of the diffusion cell temperature measurement device that can monitor the temperature of the receiving solution inside the diffusion cell in real-time;

Stirring speed ranging from 0 to 1200 rpm to meet various testing requirements;

Each diffusion cell is equipped with independent liquid level sensors, which monitor the diffusion cell liquid levels in real time, effectively preventing membrane detachment from the receiving liquid during the testing process;