Vertical Diffusion Cell Method is a standard testing method for in-vitro experiment of semi-solid dosage. Since it can be used in IVRT (In Vitro Release Testing) as well as IVPT (In Vitro Permeation Testing) as an effective method to evaluate the performance of semi-solid dosage, it is of crucial use in the development and quality control of new semi-solid dosage.
FVDT-1202A, an Automated Transdermal Diffusion System developed by FOCS, is equipped with Model A diffusion cells that comply with USP 1724 Standard. It is easy to operate and can consistently provide stable experimental results, making it a reliable apparatus for in-vitro dosage research.
The system is equipped with 12 individual vertical diffusion cells capable of automatic venting, sampling, replenishment, independent temperature measurement and control for each cell, and infrared membrane temperature testing (optional). It is an automated apparatus used to assist in the development and quality control of semi-solid dosages.
Technical Features:
Diffusion cells that comply with USP1724 Standard;
Automatic venting function to prevent sub-membrane bubbles from affecting test results;
Each diffusion cell is equipped with an independent high-precision infrared temperature sensor to monitor membrane temperature in real-time (optional);
Patented design of the diffusion cell temperature measurement device that can monitor the temperature of the receiving solution inside the diffusion cell in real-time;
Stirring speed ranging from 0 to 1200 rpm to meet various testing requirements;
Optimized design of the dosing operation device to improve the stability and reliability of dosing operations;
Different specifications of quantitative dosing rings to meet varying dosing volume requirements;
Full-sampling and partial-sampling modes to accommodate different testing needs;
High-precision sampling pumps, guaranteeing precise sampling and replenishment in different working environments;
Pool body made of PEEK and glass materials to prevent sample adsorption and ensure chemical stability under various medium conditions;
High-performance touchscreen with a user-friendly and intuitive interface;
Multi-level authorized management system and real-time operation record, fulfilling the requirements of audit trail;
patented Model A vertical diffusion cell structure, compliant with USP 1724 requirements, facilitating operation and sampling;
Online/offline dosing devices suitable for different dosing requirements;
Patented independent temperature control and heating module on each diffusion cell, ensuring precise and efficient temperature control;
Independent temperature probes on every diffusion cell, ensuring real-time measurement the temperature of the receiving solution inside the diffusion cell, with optimized temperature control algorithms to maintain temperature stability;
Fully automated tilting venting structure to meet the venting requirements of various receiving solutions (including surfactants such as SDS);
High-precision automatic sampling and replenishment.
